29976-53-2
- Product Name：N-Carbethoxy-4-piperidone
- Molecular Formula：C8H13NO3
- Purity：99%
- Molecular Weight：171.196
Product Details;
CasNo： 29976-53-2
Molecular Formula： C8H13NO3
Appearance： Clear colorless to pale yellow colored liquid
Chinese Manufacturer Supply N-Carbethoxy-4-piperidone, Export 29976-53-2 with Low Price
- Molecular Formula:C8H13NO3
- Molecular Weight:171.196
- Appearance/Colour:Clear colorless to pale yellow colored liquid
- Vapor Pressure:0.00574mmHg at 25°C
- Refractive Index:n20/D 1.475(lit.)
- Boiling Point:273.4 °C at 760 mmHg
- PKA:-1.59±0.20(Predicted)
- Flash Point:87.8 °C
- PSA：46.61000
- Density:1.155 g/cm3
- LogP:0.74570
N-Carbethoxy-4-piperidone(Cas 29976-53-2) Usage
|
Chemical Properties |
clear colorless to pale yellow colored liquid |
|
Uses |
N-Carbethoxy-4-piperidone is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. N-Carbethoxy-4-piperidone is also an Impurity of Loratadine (L469575). |
InChI:InChI=1/C8H13NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h2-6H2,1H3
29976-53-2 Relevant articles
Ecotoxic effects of loratadine and its metabolic and light-induced derivatives
Iesce, Maria Rosaria,Lavorgna, Margherita,Russo, Chiara,Piscitelli, Concetta,Passananti, Monica,Temussi, Fabio,DellaGreca, Marina,Cermola, Flavio,Isidori, Marina
, p. 664 - 672 (2019/01/03)
Loratadine and desloratadine are second-...
Development of a Robust Process for the Preparation of High-Quality 4-Methylenepiperidine Hydrochloride
Zhu, Fuqiang,Aisa, Haji A.,Zhang, Jian,Hu, Tianwen,Sun, Changliang,He, Yang,Xie, Yuanchao,Shen, Jingshan
, p. 91 - 96 (2018/02/06)
An efficient route for the preparation o...
New synthesis of (±)-2-piperazinecarboxylic acid.
JY Mérour, JY Coadou
, Tetrahedron letters, 1991
(±)-2-Piperazinecarboxylic acid is prepared from N-carbethoxy-4-piperidone by α Schmidt rearrangement followed by bromation of the lactam; then α Favorskii rearrangement on the experiment....
29976-53-2 Process route
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- 41979-39-9
4-piperidone hydrochloride
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- 541-41-3
chloroformic acid ethyl ester
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- 29976-53-2
N-ethoxycarbonyl-4-piperidone
| Conditions | Yield |
|---|---|
|
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;
|
98% |
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With triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;
|
98% |
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With sodium hydroxide; In diethyl ether; water; at 0 ℃; for 0.166667h;
|
93% |
-
- 53601-94-8
4-oxo-piperidine-1,3-dicarboxylic acid diethyl ester
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- 29976-53-2
N-ethoxycarbonyl-4-piperidone
| Conditions | Yield |
|---|---|
|
With hydrogenchloride; In ethanol; water; at 83 - 85 ℃; for 7h;
|
98.2% |
29976-53-2 Upstream products
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1445-73-4
1-Methyl-4-piperidone
-
541-41-3
chloroformic acid ethyl ester
-
41979-39-9
4-piperidone hydrochloride
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51787-77-0
1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid ethyl ester
29976-53-2 Downstream products
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53234-66-5
ethyl 1,2,3,6-tetrahydro-4-morpholino-pyridine-1-carboxylate
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19786-58-4
5-oxoazepane-1,4-dicarboxylic acid diethyl ester
-
100906-97-6
4-Benzoyloxy-4-isoquinolin-1-yl-piperidine-1-carboxylic acid ethyl ester
-
100907-00-4
4-Benzoyloxy-4-(7-methoxy-isoquinolin-1-yl)-piperidine-1-carboxylic acid ethyl ester
Relevant Products
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1-(4-Methylphenyl)-2-nitropropeneCAS：29816-55-5
-
4-oxopiperidinium chlorideCAS：41979-39-9
-
4-N-BOC-AminopiperidineCAS：73874-95-0
