5570-77-4
- Product Name：4-Chloro-N-methylpiperidine
- Molecular Formula：C6H12ClN
- Purity：99%
- Molecular Weight：133.621
Product Details;
CasNo： 5570-77-4
Molecular Formula： C6H12ClN
Quality Manufacturer Supply Best Quality 4-Chloro-N-methylpiperidine 5570-77-4 Low Price
- Molecular Formula:C6H12ClN
- Molecular Weight:133.621
- Vapor Pressure:0.293mmHg at 25°C
- Melting Point:160-165 °C
- Refractive Index:1.527
- Boiling Point:165.7 °C at 760 mmHg
- PKA:7.88±0.10(Predicted)
- Flash Point:54 °C
- PSA：3.24000
- Density:1.04 g/cm3
- LogP:1.25730
4-Chloro-N-methylpiperidine(Cas 5570-77-4) Usage
|
Chemical Properties |
Clear colorless liquid |
|
Uses |
4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist. |
|
Flammability and Explosibility |
Notclassified |
InChI:InChI=1/C5H11ClN2/c6-5-1-3-8(7)4-2-5/h5H,1-4,7H2
5570-77-4 Relevant articles
Synthesis of 3H, 13C,2H3,15N and 14C-labelled SCH 466036, a histamine 3 receptor antagonist
Hesk, David,Borges,Dumpit,Hendershot,Koharski,Lavey,McNamara,Voronin
, p. 36 - 41 (2015)
The synthesis of [3H]SCH 466036, [Me-3H3...
Process method for synthesizing N-substituted piperidine-4-boric acid
-
Paragraph 0027, (2020/06/17)
The invention relates to an organic comp...
PROCESS FOR PREPARATION OF LASMIDITAN
-
Paragraph 0186, (2020/06/01)
The present invention relates to a proce...
DIHYDROBENZOTHIOPHENES
-
Page/Page column 78-79, (2010/02/14)
The invention relates to compounds of fo...
5570-77-4 Process route
-
-
106-52-5
N-methyl-4-hydroxypiperidine
-
-
5570-77-4
4-chloro-1-methylpiperidine
| Conditions | Yield |
|---|---|
|
With
thionyl chloride; triethylamine;
In
dichloromethane;
at 20 - 40 ℃;
for 2h;
|
80% |
|
With
thionyl chloride; benzene;
|
|
|
With
thionyl chloride;
|
-
-
931-20-4
1-methylpiperidin-2-one
-
-
103057-10-9
4-chloromethyl-1-tritylimidazole
-
-
5570-77-4
4-chloro-1-methylpiperidine
| Conditions | Yield |
|---|---|
|
With
n-butyllithium; ammonia; diisopropylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate;
|
52% |
|
With
n-butyllithium; ammonia; diisopropylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate;
|
52% |
5570-77-4 Upstream products
-
106-52-5
N-methyl-4-hydroxypiperidine
-
1445-73-4
1-Methyl-4-piperidone
-
25012-72-0
ethyl 1-methyl-4-oxo-piperidin-3-carboxylate
-
6315-60-2
3,3'-methylimino-di-propionic acid diethyl ester
5570-77-4 Downstream products
-
4945-47-5
bamipine
-
102166-77-8
N-benzyl-N-(1-methyl-[4]piperidyl)-p-toluidine
-
102009-35-8
N-(4-chloro-benzyl)-N-(1-methyl-[4]piperidyl)-aniline
-
102166-98-3
N-(4-methoxy-benzyl)-N-(1-methyl-[4]piperidyl)-aniline
Relevant Products
-
Dimethylamine hydrochlorideCAS：506-59-2
-
4-Amino-1-Boc-piperidineCAS：87120-72-7
-
Tetrapeptide-5CAS：883220-97-1
